A Novel Growth Promoter for 5% Dihydropyridine Premix

Product Link for 5% Dihydropyridine Premix

This is a commonly used feed additive in the animal husbandry industry. The following is a comprehensive analysis covering its definition, mechanism of action, main functions, applications, usage methods, and precautions.

What is it?

Dihydropyridine: A compound with the chemical name 2,6-Dimethyl-3,5-diethyl ester-1,4-dihydropyridine. It is a novel antioxidant and growth promoter.

Premix: Refers to a preparation made by uniformly mixing one or more trace components (such as vitamins, minerals, drugs, additives) with a suitable carrier or diluent. The purpose is to ensure even distribution when mixed into large quantities of compound feed.

5%: This indicates that the content of the active ingredient, dihydropyridine, in this premix is 5%. That means every 100 grams of the premix contains 5 grams of pure dihydropyridine; the remaining 95% is the carrier (such as calcium carbonate, bran, etc.).

Therefore, the 5% Dihydropyridine Premix is a low-concentration, convenient form of dihydropyridine designed for easy addition to feed.

Mechanism of Action

The primary mechanism of dihydropyridine is its antioxidant property. It inhibits the peroxidation of polyunsaturated fatty acids within organisms (especially on cell membranes) and scavenges free radicals, thereby:

1.Protecting Cell Membrane Structure: Maintains the integrity and functionality of cell membranes, enhancing cell vitality.

2.Increasing Endocrine Hormone Levels: Through its antioxidant effect, it reduces oxidative damage to endocrine glands like the hypothalamus, pituitary gland, and gonads, promoting the normal secretion of hormones such as follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone.

3.Improving Nutrient Utilization: Protects easily oxidized components in feed, such as vitamins and fats, enhancing their biological availability.

Main Functions and Uses

Based on the above mechanism, the 5% Dihydropyridine Premix primarily demonstrates the following efficacy in animal production:

Promotes Growth and Increases Daily Weight Gain: Mainly used in economic animals like pigs, broilers, beef cattle, and fattening sheep to improve feed conversion ratio and shorten the rearing cycle.

Improves Reproductive Performance:

Breeding Males: Improves semen quality (sperm density, motility) and extends semen storage time.

Females: Promotes ovulation, increases conception rate, litter size, and lambing rate.

Enhances Immunity: Boosts the animal’s resistance to stress (e.g., heat stress, transport stress), reducing morbidity and mortality.

Improves Product Quality: Can somewhat improve the quality of meat, eggs, and milk.

Applicable Animals

Poultry: Broilers, layers, breeding chickens, ducks, geese, etc.

Pigs: Piglets, growing-finishing pigs, sows, boars.

Ruminants: Dairy cows, beef cattle, breeding cattle, sheep, etc.

Aquatic Animals: Fish, shrimp, etc.

Others: Special economic animals (e.g., mink, fox, raccoon dog), etc.

Usage Method and Dosage

Crucial: Must be used strictly according to the product instructions or veterinary guidance. Recommended dosages may vary slightly between different manufacturers’ products.

Addition Method: Mix evenly with other feed ingredients through gradual dilution to finally produce complete compound feed.

Recommended Dosage (based on the active ingredient, pure dihydropyridine):

Livestock and Poultry: Add 100-150 grams of pure dihydropyridine per 1000 kg of complete feed.

Conversion to 5% Premix: Because the premix contains only 5% active ingredient, the amount of premix needed is 20 times that of the pure product.

That is: Add 2-3 kg of the 5% Dihydropyridine Premix per 1000 kg of feed.

Example: To prepare 1 ton (1000 kg) of feed, add 2000 to 3000 grams of the 5% premix.

Precautions

1.Thorough Mixing: Must be thoroughly and evenly mixed into the feed to avoid local overdosing or underdosing.

2.Withdrawal Period: Generally, dihydropyridine is highly safe and metabolizes quickly, so a withdrawal period is usually not required. However, it’s best to follow the specific product label instructions.

3.Compatibility Contraindications: No clear compatibility contraindications have been reported, but it’s advisable to consult a professional when using it concurrently with other additives.

4.Storage: Store sealed, protected from light, in a cool, dry place. Although dihydropyridine itself is an antioxidant, the carrier in its premix may be prone to moisture absorption and caking.

5.Quality Selection: Choose products from reputable manufacturers with guaranteed quality to ensure accurate active ingredient content and uniform mixing.

Summary

The 5% Dihydropyridine Premix is an efficient, safe, and economical feed additive. Through its powerful antioxidant action, it significantly promotes animal growth, improves reproductive performance, and enhances immunity. Correct usage can bring significant economic benefits to farmers. The most critical point when using it is to accurately calculate the addition amount, ensuring the dosage of the active ingredient (pure dihydropyridine) is within the recommended range.